Hair loss is a condition that affects both appearance and self-confidence, leading many individuals to seek effective, safe solutions without resorting to surgery. Regenera Activa is a cutting-edge hair-loss treatment that stimulates dormant hair follicles. It utilizes autologous stem cells to naturally restore hair growth, increase hair density, and enhance overall hair quality. This procedure is performed without major surgical intervention and requires minimal recovery time
What is the Regenera Activa?
Regenera Activa is an advanced regenerative medical treatment for hair loss and weak follicles, based on extracting autologous stem cells from the patient’s own scalp, which are then reinjected into the affected areas to stimulate natural hair regrowth. The technique is non-invasive and is usually performed in a single session lasting about an hour, in which precise skin samples are taken from the follicle-rich area (often the back of the head), treated with a special device to extract stem cells and growth-promoting factors, and then injected into the areas suffering from hair loss.
Regenera Activa aims to stimulate weak and dormant follicles without the need for a conventional hair transplant. It is safe, chemical-free, and has few side effects because it relies on the patient’s own cells.
How does the Regenera Activa work?
The Regenera Activa technique is performed through the following steps:
- Initial patient assessment: The doctor assesses the condition of the scalp, the extent of hair loss, and the stage of baldness (Hamilton Scale for men or Ludwig Scale for women) to make sure the follicles are still active or stimulable, and to make sure there are no scalp diseases or conditions that prevent the procedure.
- A small sample of skin is taken: Local anesthesia is injected into the area where the follicles will be extracted, typically from the scalp behind the ear, due to the rarity of hair diseases and conditions in this area, particularly male pattern alopecia. Three to four small samples, each measuring 2.5 mm in diameter, are collected without causing any pain.
- Sample Processing:
- The Regenera device activa contains a specific scalp sample (including hair follicles and surrounding skin) without saline. At this stage, microscopic stem cells and growth factors that are responsible for stimulating hair growth and reducing hair loss are extracted due to their ability to divide and regenerate.
- The tissue is crushed and then filtered through fine filters to obtain a concentrated solution known as cellular concentrate, which is a blend of potent autologous stem cells, growth factors, and microstem cells, ready for injection into the affected areas.
- Injection of cellular suspension into the affected areas: The cellular suspension, containing stem cells and stimulating factors, is injected into the scalp in areas of hair loss or thinning using fine needles. The goal for these cells is to stimulate existing follicles to stimulate hair growth.
The procedure usually takes 30 to 60 minutes. It is possible to return to everyday life immediately after the Regenera Activa session, so there is no need for any rest or recovery period.
What does the sample tell us?
The following substances are extracted from the sample:
- Autologous stem cells: Cells capable of regenerating and secreting factors that stimulate other cells.
- Growth factors: Proteins that help stimulate the follicles and optimize their environment (blood supply, nutrition, oxygen).
- Microscopic cells: Small cellular parts, other than whole cells, that may include support cells, metabolic cells, and cells that help regulate the cellular environment.
How do these cells stimulate dormant or weakened follicles to grow?
These cells stimulate the growth of dormant or weakened follicles by:
- Stimulation of stem cells leads to the release of growth factors that help revitalize weak or dormant follicles, restarting the hair growth cycle
- Strengthening the blood supply in the scalp, which improves the nutrition and oxygen supply to the follicles
- Optimize the cellular environment of the scalp in terms of support and nutrition, as transplanted cells help strengthen existing follicles, reduce shedding, and increase density
Linking the mechanism to the expected results of the Regenera Activa technique
- Hair thickening: After the injections, as follicles are stimulated and blood circulation improves, hair in the treated areas is expected to become thicker.
- Prevention of shedding: The technique helps inhibit or slow hair loss, especially in the early to middle stages of baldness.
- Follicle regeneration: Reactivating follicles that have been dormant or weakened, leading to new hair growth in some cases or improving the growth of existing hair.
Candidates for treatment with the Regenera Activa technique
Candidates for treatment with Regenera Activa include:
- Those suffering from hair loss due to external or hormonal factors, provided the hair follicles are still stimulable
- Men and women with hereditary hair loss in the early to middle stages
- People who don’t want to undergo a surgical procedure, such as a hair transplant
- Those looking for a natural and safe solution using their own cells without artificial intervention
- Cases in which hair follicles are still present but are weak or dormant
- Patients who want to increase hair density, improve hair thickness, or slow down hair loss
- People who have had hair transplants and want to optimize the results
- People who have thinning hair but not complete baldness
Cases not suitable for the Regenera Activa technique
Several conditions are not candidates for the Regenera Activa technique, including:
- Complete baldness (no stimulable follicles)
- Immune alopecia and skin psoriasis
- Scalp infections, fungus, or folliculitis
- Stress-induced or traumatic hair loss
- Pregnant women (but safe during lactation)
- Cases where the actual cause of hair loss has not yet been assessed
Features and benefits of the Regenera Activa technique
The Regenera Activa has many benefits, making this technique more effective and safer. Features include:
- Minimizes and reduces scalp inflammation
- The procedure takes approximately 60 minutes
- Safe and FDA-approved
- It is done in one session with no pain or surgery
- Fast results in a few weeks
- Suitable for both men and women
- Natural-looking, long-lasting results
- Autologous injections from the body without the risk of allergic reactions
- No recovery time is required, and the patient can return to everyday life the same day
- The safest technique, where stem cells from the patient’s own body are used
- It is a fast and effective technique that involves rapid preparation and natural tissue breakdown

Potential risks of the Regenera Activa technique
Potential risks when treated with the Regenera Activa technique include:
- Temporary inflammation of the scalp
- Initial temporary shedding of some hairs (may occur as part of the regeneration process)
- May not achieve satisfactory results in some cases (not guaranteed results)
- Delayed or limited response on a case-by-case basis (depends on the number of remaining follicles, patient’s health, nutrition, and genetic factors)
To minimize these risks, choosing an experienced and specialized doctor is vital. Ensuring the procedure is performed correctly, providing careful follow-up after the session, and applying preventive measures such as sterilization and special post-procedure advice increase the chances of successful treatment and protect the scalp from complications.
Comparison of the Regenera Activa technique and other hair loss treatments
There are several differences between the Regenera Activa technique and other hair loss treatments:
Difference between the Regenera Activa technique and PRP injections
The following table compares the Regenera activa technique with platelet-rich plasma (PRP) injections:
| Criterion | The Regenera Activa technique | Plasma (PRP) |
|---|---|---|
| Ingredients | A solution containing autologous stem cells and growth factors | High concentration of platelets and growth factors taken from the patient’s blood |
| Objective | Stimulate dormant follicles and produce new ones | Revitalize existing hair and improve blood circulation |
| Number of sessions | One session is often enough for most cases | Usually, several sessions are required to maintain results |
| Results | Hair thickening and follicle regeneration | Promote the growth of existing hair and increase density |
| Source material | Hair follicles or stem cell areas taken from the same hair follicles or other areas | Platelets taken from the patient’s blood |
| Integration | Can be combined with PRP for better results | Can be combined with the Regenera Activa technique for better results |
The difference between the Regenera Activa technique and hair transplant
The following table shows a comparison between the Regenera activa technique and hair transplant:
| Criterion | The Regenera Activa technique | Hair transplant |
|---|---|---|
| Mechanism | Stimulate and revitalize existing follicles | Transferring follicles from a dense area to bald areas |
| Objective | Revitalize dormant and weakened follicles | Filling empty areas with hair from other areas |
| Suitable cases | Partial hereditary hair loss, weak follicles, desire to avoid surgery | Complete baldness or extensive hair loss |
| Number of sessions | Usually one session | Requires one or more sessions, depending on the extent of baldness |
| Combining the two technologies | Possible to improve hair density and speed up results | Possible when needed to compensate for large bald spots |
The Regenera Activa technique results and how long they take to appear
Regenera results appear gradually over weeks, peaking after several months, depending on the hair’s response and individual factors:

When do the results start to show?
- Week 4 to 6: Some patients may begin to notice a slight improvement in hair density.
- 3 to 6 months: Final results begin to appear, with a noticeable improvement in hair density and quality.
- 6 months: Noticeable improvement in hair density and quality.
- 12 to 18 months: Final results are visible, with thicker, healthier hair.
Continued results and the need for supplemental sessions
- One session is usually enough to achieve results
- Maintenance sessions may be necessary every 12 to 18 months to maintain results
Factors affecting the speed of results
There are many factors that affect the speed of results, including:
- Age: Age-related hormonal changes may affect the effectiveness of treatment.
- nutrition: A balanced diet supports hair health.
- Lifestyle: Stress and lack of sleep can take their toll.
- Genetic factors: May affect treatment response.
- Scalp health: A healthy scalp contributes to better results.
Tips before and after the Regenera Activa procedure
The patient must prepare before the Regenera treatment and adhere to the post-treatment hair care tips.
Preparations before the Regenera Activa treatment
- Stopping certain medications or supplements
- The physician sometimes recommends discontinuing certain medications or supplements, such as anti-inflammatories or specific vitamins, that may affect blood clotting or scalp health, to ensure the safety and success of the procedure
- Conducting the necessary examinations:
- Before the injection, the patient may be asked to undergo tests to evaluate the scalp and make sure there are no infections or diseases that would prevent the procedure
- This includes assessing the number of remaining follicles and the health of the scalp, to make sure the treatment will be effective
- Consider the health of the scalp and hair:
- The scalp must be clean and free from harmful chemicals or harsh dyes prior to the session
- It is advisable to minimize anxiety and stress, as scalp health directly impacts the results
- Avoid substances or habits that may irritate the scalp, such as recent hair dyes or aggressive styling techniques
Hair care tips after Regenera Activa treatment
- Scalp care:
- Gently wash the hair using a suitable, natural shampoo after the period specified by the physician
- Avoid direct and intense exposure to sunlight during the first few weeks following the treatment
- Avoid strong chemical dyes or irritating substances for a period specified by the physician
- Using hair tools:
- Reduce the use of heat-styling tools, such as flat irons or blow-dryers
- Avoid vigorous brushing or pulling the hair during the first few weeks
- Medical follow-up:
- Adhere to follow-up visits with the physician to assess treatment results
- Undergo maintenance or supplementary sessions, if recommended by the physician
- Patience and observing the results:
- Hair growth takes time, so be patient and observe the gradual development of hair density and quality
- Regular monitoring and gentle cleansing of the scalp helps to maximize results and prevent irritation
In conclusion, Regenera Activa is an advanced option for treating hair loss in a non-surgical, natural way. To ensure the best results, it is important to choose an experienced doctor and perform a thorough examination of the case before the procedure. If you are experiencing hair loss, it is advisable to seek medical advice to assess whether this technique is suitable and can be used safely and effectively to achieve the desired results.
Sources:
- Zari, S. (2021). Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study. Clinical, Cosmetic and Investigational Dermatology, (eCollection 2021), 1725-1736.
- Justicz, N., Derakhshan, A., Chen, J. X., & Lee, L. N. (2020). Platelet-Rich Plasma for Hair Restoration. Facial Plastic Surgery Clinics of North America, 28(2), 181-187.
